2019年12月，美國環保署(U.S. EPA)根據毒性物質控制法案(Toxic Substances Control Act, TSCA)開始對20個物質進行風險評估，並於2020年4月釋出初步結果。收集完各界的評論，美國環保署於2020年8月釋出針對評論的回覆與各物質最終完整評估報告。20個物質如下：
| CAS RN | 物質英文名稱 |
| 106-99-0 | 1,3-Butadiene |
| 106-46-7 | p-Dichlorobenzene (Benzene, 1,4-dichloro-) |
| 75-34-3 | 1,1-Dichloroethane |
| 107-06-2 | 1,2-Dichloroethane |
| 156-60-5 | trans-1,2- Dichloroethylene |
| 78-87-5 | 1,2-Dichloropropane |
| 106-93-4 | Ethylene dibromide (Ethane, 1,2-dibromo-) |
| 1222-05-5 | 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta [g]-2-benzopyran (HHCB) |
| 79-94-7 | 4,4′-(1-Methylethylidene)bis[2, 6-dibromophenol] (TBBPA) |
| 115-86-6 | Triphenyl Phosphate (TPP) |
| 79-00-5 | 1,1,2-Trichloroethane |
| 115-96-8 | Tris(2-chloroethyl) phosphate (TCEP) |
| 117-81-7 | Diethylhexyl Phthalate |
| 84-61-7 | Dicyclohexyl Phthalate |
| 84-69-5 | Diisobutyl Phthalate |
| 85-68-7 | Butyl Benzyl Phthalate |
| 84-74-2 | Dibutyl Phthalate |
| 85-44-9 | Phthalic Anhydride |
| 95-50-1 | o-Dichlorobenzene (Benzene, 1,2-dichloro-) |
| 50-00-0 | Formaldehyde |
詳細評估結果、美國環保署對收到的評論所做的回應，可在此網址查看：https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/final-scope-documents-high-priority-chemicals-undergoing